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Advanced identification of global bioactivity hotspots via screening of the metabolic fingerprint of entire ecosystems
Natural products (NP) are a valuable drug resource. However, NP-inspired drug leads are declining, among other reasons due to high re-discovery rates. We developed a conceptual framework using the metabolic fingerprint of entire ecosystems (MeE) to facilitate the discovery of global bioactivity hots...
Autores principales: | Mueller, Constanze, Kremb, Stephan, Gonsior, Michael, Brack-Werner, Ruth, Voolstra, Christian R., Schmitt-Kopplin, Philippe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987164/ https://www.ncbi.nlm.nih.gov/pubmed/31992728 http://dx.doi.org/10.1038/s41598-020-57709-0 |
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