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Understanding the Complexity of the Tumor Microenvironment in K-ras Mutant Lung Cancer: Finding an Alternative Path to Prevention and Treatment

Kirsten rat sarcoma viral oncogene (K-ras) is a well-documented, frequently mutated gene in lung cancer. Since K-ras regulates numerous signaling pathways related to cell survival and proliferation, mutations in this gene are powerful drivers of tumorigenesis and confer prodigious survival advantage...

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Detalles Bibliográficos
Autores principales: Deng, Shanshan, Clowers, Michael J., Velasco, Walter V., Ramos-Castaneda, Marco, Moghaddam, Seyed Javad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987304/
https://www.ncbi.nlm.nih.gov/pubmed/32039025
http://dx.doi.org/10.3389/fonc.2019.01556

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