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Understanding the Complexity of the Tumor Microenvironment in K-ras Mutant Lung Cancer: Finding an Alternative Path to Prevention and Treatment
Kirsten rat sarcoma viral oncogene (K-ras) is a well-documented, frequently mutated gene in lung cancer. Since K-ras regulates numerous signaling pathways related to cell survival and proliferation, mutations in this gene are powerful drivers of tumorigenesis and confer prodigious survival advantage...
Autores principales: | Deng, Shanshan, Clowers, Michael J., Velasco, Walter V., Ramos-Castaneda, Marco, Moghaddam, Seyed Javad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987304/ https://www.ncbi.nlm.nih.gov/pubmed/32039025 http://dx.doi.org/10.3389/fonc.2019.01556 |
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