Identification of a Selective PDE4B Inhibitor From Bryophyllum pinnatum by Target Fishing Study and In Vitro Evaluation of Quercetin 3-O-α-L-Arabinopyranosyl-(1→2)-O-α-L-Rhamnopyranoside

Natural products are considered an important source of bioactive compounds especially in biodiversity-rich countries like Brazil. The identification of potential targets is crucial to the development of drugs from natural sources. In this context, in silico methodologies, such as inverse virtual scr...

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Detalles Bibliográficos
Autores principales: Lourenço, Estela M. G., Fernandes, Júlia M., Carvalho, Vinícius de F., Grougnet, Raphael, Martins, Marco A., Jordão, Alessandro K., Zucolotto, Silvana M., Barbosa, Euzébio G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987432/
https://www.ncbi.nlm.nih.gov/pubmed/32038254
http://dx.doi.org/10.3389/fphar.2019.01582

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