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Nuclear and Cytoplasmatic Quantification of Unconjugated, Label-Free Locked Nucleic Acid Oligonucleotides

Methods for the quantification of antisense oligonucleotides (AONs) provide insightful information on biodistribution and intracellular trafficking. However, the established methods have not provided information on the absolute number of molecules in subcellular compartments or about how many AONs a...

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Detalles Bibliográficos
Autores principales:	Pendergraff, Hannah, Schmidt, Steffen, Vikeså, Jonas, Weile, Christian, Øverup, Charlotte, W. Lindholm, Marie, Koch, Troels
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mary Ann Liebert, Inc., publishers 2020
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987631/ https://www.ncbi.nlm.nih.gov/pubmed/31618108 http://dx.doi.org/10.1089/nat.2019.0810

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