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Synthesis of [3,3-(2)H(2)]-Dihydroartemisinic Acid to Measure the Rate of Nonenzymatic Conversion of Dihydroartemisinic Acid to Artemisinin

[Image: see text] Dihydroartemisinic acid is the biosynthetic precursor to artemisinin, the endoperoxide-containing natural product used to treat malaria. The conversion of dihydroartemisinic acid to artemisinin is a cascade reaction that involves C–C bond cleavage, hydroperoxide incorporation, and...

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Detalles Bibliográficos
Autores principales:	Varela, Kaitlyn, Arman, Hadi D., Yoshimoto, Francis K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society and American Society of Pharmacognosy 2019
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988128/ https://www.ncbi.nlm.nih.gov/pubmed/31859509 http://dx.doi.org/10.1021/acs.jnatprod.9b00686

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