Cargando…

Establishment of the circadian metabolic phenotype strategy in spontaneously hypertensive rats: a dynamic metabolomics study

BACKGROUND: Circadian rhythms play a fundamental role in the progression of cardiovascular events. Almost all cardiovascular diseases have a circadian misalignment usually characterized by changes in metabolites. This study aimed to dynamically monitor rhythmic biomarkers, to elucidate the metabolic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Huanjun, Wang, Xiaoming, Qi, Dongmei, Sun, Mengjia, Hou, Qingqing, Li, Yunlun, Jiang, Haiqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988197/ https://www.ncbi.nlm.nih.gov/pubmed/31992312 http://dx.doi.org/10.1186/s12967-020-02222-1

Ejemplares similares

Targeted neurotransmitter metabolomics profiling of oleanolic acid in the treatment of spontaneously hypertensive rats
por: Yu, Ruixue, et al.
Publicado: (2019)

Antihypertensive activity of oleanolic acid is mediated via downregulation of secretory phospholipase A(2) and fatty acid synthase in spontaneously hypertensive rats
por: Zhang, Shiming, et al.
Publicado: (2020)

Serum Metabolomics Study Based on LC-MS and Antihypertensive Effect of Uncaria on Spontaneously Hypertensive Rats
por: Liu, Ana, et al.
Publicado: (2018)

Intervention of Uncaria and Its Components on Liver Lipid Metabolism in Spontaneously Hypertensive Rats
por: Tian, Zhenhua, et al.
Publicado: (2020)

Effect of Yishenjiangyafang on Plasma Metabolomics in Senile Spontaneously Hypertensive Rats
por: Zhang, Lei, et al.
Publicado: (2021)

Metabonomics Study of Essential Hypertension and Its Chinese Medicine Subtypes by Using Gas Chromatography-Mass Spectrometry and Nuclear Magnetic Resonance Spectroscopy
por: Li, Yunlun, et al.
Publicado: (2013)

Decompression Mechanism of Radish Seed in Prehypertension Rats through Integration of Transcriptomics and Metabolomics Methods
por: Jia, Qiang, et al.
Publicado: (2023)

Metabolomics of Artichoke Bud Extract in Spontaneously Hypertensive Rats
por: Wang, Zhi-Bin, et al.
Publicado: (2021)

Metabolomics Research Reveals the Mechanism of Action of Astragalus Polysaccharide in Rats with Digestive System Disorders
por: Wang, Huanjun, et al.
Publicado: (2018)

Correction to “Metabolomics of Artichoke Bud Extract in Spontaneously Hypertensive Rats”
por: Wang, Zhi-Bin, et al.
Publicado: (2021)

Deciphering the pharmacological mechanisms of Chaenomeles Fructus against rheumatoid arthritis by integrating network pharmacology and experimental validation
por: Sun, Mengjia, et al.
Publicado: (2022)

Identification of Tengfu Jiangya Tablet Target Biomarkers with Quantitative Proteomic Technique
por: Xu, Jingwen, et al.
Publicado: (2017)

Circadian Metabolomics in Time and Space
por: Dyar, Kenneth A., et al.
Publicado: (2017)

Gut Microbiota Variation With Short-Term Intake of Ginger Juice on Human Health
por: Wang, Xiaolong, et al.
Publicado: (2021)

Early Chronotype and Tissue-Specific Alterations of Circadian Clock Function in Spontaneously Hypertensive Rats
por: Sládek, Martin, et al.
Publicado: (2012)

Dissecting the Metabolic Phenotype of the Antihypertensive Effects of Five Uncaria Species on Spontaneously Hypertensive Rats
por: Feng, Zijin, et al.
Publicado: (2019)

Discovery of Biomarkers and Potential Mechanisms of Agarwood Incense Smoke Intervention by Untargeted Metabolomics and Network Pharmacology
por: Dong, Meiyue, et al.
Publicado: (2022)

Diurnal Circadian Lighting Accumulation Model: A Predictor of the Human Circadian Phase Shift Phenotype
por: Hou, Dandan, et al.
Publicado: (2022)

Eplerenone restores 24-h blood pressure circadian rhythm and reduces advanced glycation end-products in rhesus macaques with spontaneous hypertensive metabolic syndrome
por: Zhang, Yan, et al.
Publicado: (2016)

Efficacy and safety of Tengfu Jiangya tablet combined with valsartan/amlodipine in the treatment of stage 2 hypertension: study protocol for a randomized controlled trial
por: Wang, Yu, et al.
Publicado: (2022)

Unusual circadian hypertension associated with polydipsia
por: Bohlender, Jürgen M, et al.
Publicado: (2016)

Therapeutic value of the metabolomic active neurotransmitter isorhynchophylline in the treatment of spontaneously hypertensive rats by regulating neurotransmitters
por: Alharbi, Homood, et al.
Publicado: (2021)

Placental circadian lincRNAs and spontaneous preterm birth
por: Zhou, Guoli, et al.
Publicado: (2023)

Circadian rhythm in restless legs syndrome
por: Tang, Mingyang, et al.
Publicado: (2023)

Natural drugs targeting inflammation pathways can be used to treat atherosclerosis
por: Song, Xiayinan, et al.
Publicado: (2022)

Metabolomics strategies to discover new biomarkers associated to severe allergic phenotypes
por: Barber, Domingo, et al.
Publicado: (2019)

Profiling of the circadian metabolome in thioacetamide‐induced liver cirrhosis in mice
por: Fujisawa, Koichi, et al.
Publicado: (2017)

Exposure to atmospheric pollutants is associated with alterations of gut microbiota in spontaneously hypertensive rats
por: Chen, Dongmei, et al.
Publicado: (2019)

Novel high-coverage targeted metabolomics method (SWATHtoMRM) for exploring follicular fluid metabolome alterations in women with recurrent spontaneous abortion undergoing in vitro fertilization
por: Song, Jingyan, et al.
Publicado: (2019)

LC–MS-based lipidomic analysis of liver tissue sample from spontaneously hypertensive rats treated with extract hawthorn fruits
por: Sun, Luping, et al.
Publicado: (2022)

Evaluation of circadian phenotypes utilizing fibroblasts from patients with circadian rhythm sleep disorders
por: Hida, A, et al.
Publicado: (2017)

The circadian rhythm of bladder clock genes in the spontaneously hypersensitive rat
por: Kimura, Yusuke, et al.
Publicado: (2019)

Genome-wide association of sleep and circadian phenotypes
por: Gottlieb, Daniel J, et al.
Publicado: (2007)

Mood phenotypes in rodent models with circadian disturbances
por: Imamura, Kiyomichi, et al.
Publicado: (2022)

Circadian Variation of the Human Metabolome Captured by Real-Time Breath Analysis
por: Martinez-Lozano Sinues, Pablo, et al.
Publicado: (2014)

Establishment and experimental validation of a novel cuproptosis-related gene signature for prognostic implication in cholangiocarcinoma
por: Chen, Jialu, et al.
Publicado: (2022)

Increased Sensitivity of the Circadian System to Temporal Changes in the Feeding Regime of Spontaneously Hypertensive Rats - A Potential Role for Bmal2 in the Liver
por: Polidarová, Lenka, et al.
Publicado: (2013)

Integrated Proteomics and Metabolomics Analysis in Pregnant Rat Hippocampus After Circadian Rhythm Inversion
por: Lin, Jingjing, et al.
Publicado: (2022)

Dissecting the Regulation of Arachidonic Acid Metabolites by Uncaria rhynchophylla (Miq). Miq. in Spontaneously Hypertensive Rats and the Predictive Target sEH in the Anti-Hypertensive Effect Based on Metabolomics and Molecular Docking
por: Gao, Lei, et al.
Publicado: (2022)

Integrative analysis of the mouse fecal microbiome and metabolome reveal dynamic phenotypes in the development of colorectal cancer
por: Liu, Jingjing, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_h44g3qf4688j785hoecphi4dd1