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Combination therapy with Olaratumab/doxorubicin in advanced or metastatic soft tissue sarcoma -a single-Centre experience
BACKGROUND: The antibody targeting platelet-derived growth factor receptor alpha (PDGFRA), olaratumab, was approved in 2016 for metastatic soft tissue sarcoma (STS) in combination with doxorubicin based on promising results of a phase Ib/II trial by the Food and Drug Administration (FDA). However, r...
Autores principales: | Striefler, Jana Käthe, Brandes, Franziska, Baur, Alexander, Pfitzner, Berit Maria, Kaul, David, Rau, Daniel, Dörr, Anne, Schmiester, Maren, Koulaxouzidis, Georgios, Bullinger, Lars, Märdian, Sven, Flörcken, Anne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988236/ https://www.ncbi.nlm.nih.gov/pubmed/31996176 http://dx.doi.org/10.1186/s12885-020-6551-y |
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