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Hc-hrg-2, a glutathione transferase gene, regulates heme homeostasis in the blood-feeding parasitic nematode Haemonchus contortus

BACKGROUND: Haemonchus contortus, a blood-feeding parasite, is constantly surrounded by large quantities of heme released from the catabolism of host red blood cells. To cope with the toxicity of free heme, H. contortus needs to uptake and detoxify the heme, a process believed to be paramount for pa...

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Detalles Bibliográficos
Autores principales: Zhou, Jing-Ru, Bu, Dan-Ru, Zhao, Xian-Feng, Wu, Fei, Chen, Xue-Qiu, Shi, Heng-Zhi, Yao, Chao-Qun, Du, Ai-Fang, Yang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988263/
https://www.ncbi.nlm.nih.gov/pubmed/31996262
http://dx.doi.org/10.1186/s13071-020-3911-z

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