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NFкB is a critical transcriptional regulator of atypical cadherin FAT1 in glioma

BACKGROUND: Overexpression of FAT1 gene and its oncogenic effects have been reported in several cancers. Previously, we have documented upregulation of FAT1 gene in glioblastoma (GBM) tumors which was found to increase the expression of proinflammatory markers, HIF-1α, stemness genes and EMT markers...

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Detalles Bibliográficos
Autores principales: Srivastava, Chitrangda, Irshad, Khushboo, Gupta, Yakhlesh, Sarkar, Chitra, Suri, Ashish, Chattopadhyay, Parthaprasad, Sinha, Subrata, Chosdol, Kunzang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988320/
https://www.ncbi.nlm.nih.gov/pubmed/31992226
http://dx.doi.org/10.1186/s12885-019-6435-1