Cargando…
Antibacterial activity of human mesenchymal stem cells mediated directly by constitutively secreted factors and indirectly by activation of innate immune effector cells
Mesenchymal stem cells (MSC) have been shown to improve wound healing and suppress inflammatory immune responses. Newer research also indicates that MSC exhibit antimicrobial activity, although the mechanisms underlying this activity have not been fully elucidated. Therefore, we conducted in vitro a...
Autores principales: | Chow, Lyndah, Johnson, Valerie, Impastato, Renata, Coy, Jonathan, Strumpf, Alyssa, Dow, Steven |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988770/ https://www.ncbi.nlm.nih.gov/pubmed/31702119 http://dx.doi.org/10.1002/sctm.19-0092 |
Ejemplares similares
-
Mesenchymal stromal cell‐secreted CCL2 promotes antibacterial defense mechanisms through increased antimicrobial peptide expression in keratinocytes
por: Marx, Charlotte, et al.
Publicado: (2021) -
Immune Activated Cellular Therapy for Drug Resistant Infections: Rationale, Mechanisms, and Implications for Veterinary Medicine
por: Pezzanite, Lynn M., et al.
Publicado: (2022) -
Distinct differences in immunological properties of equine orthobiologics revealed by functional and transcriptomic analysis using an activated macrophage readout system
por: Pezzanite, Lynn M., et al.
Publicado: (2023) -
The mesenchymal stromal cell secretome impairs methicillin‐resistant Staphylococcus aureus biofilms via cysteine protease activity in the equine model
por: Marx, Charlotte, et al.
Publicado: (2020) -
Magnetic targeting increases mesenchymal stromal cell retention in lungs and enhances beneficial effects on pulmonary damage in experimental silicosis
por: Silva, Luisa H. A., et al.
Publicado: (2020)