Cargando…

Transcriptional Profiling of Non-injured Nociceptors After Spinal Cord Injury Reveals Diverse Molecular Changes

Traumatic spinal cord injury (SCI) has devastating implications for patients, including a high predisposition for developing chronic pain distal to the site of injury. Chronic pain develops weeks to months after injury, consequently, patients are treated after irreparable changes have occurred. Noci...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yasko, Jessica R., Moss, Isaac L., Mains, Richard E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988781/ https://www.ncbi.nlm.nih.gov/pubmed/32038157 http://dx.doi.org/10.3389/fnmol.2019.00284

Ejemplares similares

Repair of the Injured Spinal Cord by Schwann Cell Transplantation
por: Fu, Haitao, et al.
Publicado: (2022)

Gene Expression Profiling of Cutaneous Injured and Non-Injured Nociceptors in SNI Animal Model of Neuropathic Pain
por: Berta, Temugin, et al.
Publicado: (2017)

The Role and Modulation of Spinal Perineuronal Nets in the Healthy and Injured Spinal Cord
por: Sánchez-Ventura, Judith, et al.
Publicado: (2022)

Gene Expression Profiling in the Injured Spinal Cord of Trachemys scripta elegans: An Amniote with Self-Repair Capabilities
por: Valentin-Kahan, Adrián, et al.
Publicado: (2017)

Defining the nociceptor transcriptome
por: Thakur, Matthew, et al.
Publicado: (2014)

Passive Clearing and 3D Lightsheet Imaging of the Intact and Injured Spinal Cord in Mice
por: McCreedy, Dylan A., et al.
Publicado: (2021)

Modulation of Respiratory System by Limb Muscle Afferents in Intact and Injured Spinal Cord
por: Shevtsova, Natalia A., et al.
Publicado: (2019)

Molecular Expression Profile of Changes in Rat Acute Spinal Cord Injury
por: Wang, Jun-Juan, et al.
Publicado: (2021)

Chloride – The Underrated Ion in Nociceptors
por: Wilke, Bettina U., et al.
Publicado: (2020)

Plasticity of the Injured Human Spinal Cord: Insights Revealed by Spinal Cord Functional MRI
por: Cadotte, David W., et al.
Publicado: (2012)

Propriospinal Neurons: Essential Elements of Locomotor Control in the Intact and Possibly the Injured Spinal Cord
por: Laliberte, Alex M., et al.
Publicado: (2019)

Plasticity of the Injured Spinal Cord
por: Guérout, Nicolas
Publicado: (2021)

Dynamic Diversity of Glial Response Among Species in Spinal Cord Injury
por: Perez, Jean-Christophe, et al.
Publicado: (2021)

PRDM12 Is Transcriptionally Active and Required for Nociceptor Function Throughout Life
por: Kokotović, Tomislav, et al.
Publicado: (2021)

Sparse genetic tracing reveals regionally specific functional organization of mammalian nociceptors
por: Olson, William, et al.
Publicado: (2017)

Brainstem-Evoked Transcription of Defensive Genes After Spinal Cord Injury
por: Jermakowicz, Walter J., et al.
Publicado: (2019)

Motor unit firing rates during spasms in thenar muscles of spinal cord injured subjects
por: Zijdewind, Inge, et al.
Publicado: (2014)

Neurogenesis potential of oligodendrocyte precursor cells from oligospheres and injured spinal cord
por: Zhao, Qing, et al.
Publicado: (2022)

Microglia Stimulation by Protein Extract of Injured Rat Spinal Cord. A Novel In vitro Model for Studying Activated Microglia
por: Hernández, Joaquim, et al.
Publicado: (2021)

Nociceptors as chronic drivers of pain and hyperreflexia after spinal cord injury: an adaptive-maladaptive hyperfunctional state hypothesis
por: Walters, Edgar T.
Publicado: (2012)

EPAC1 and EPAC2 promote nociceptor hyperactivity associated with chronic pain after spinal cord injury
por: Berkey, Samantha C., et al.
Publicado: (2019)

Nociceptor activity induces nonionotropic NMDA receptor signaling to enable spinal reconsolidation and reverse pathological pain
por: Zhang, Hantao, et al.
Publicado: (2023)

The spinal cord injured patient : comprehensive management
Publicado: (1991)

Energy Expenditure Estimation During Crutch-Orthosis-Assisted Gait of a Spinal-Cord-Injured Subject
por: Michaud, Florian, et al.
Publicado: (2019)

Pyroptosis in spinal cord injury
por: Yin, Jian, et al.
Publicado: (2022)

Tracheostomy in Spinal Cord Injured Patients
por: Ganuza, Javier-Romero, et al.
Publicado: (2011)

Integrated transcriptomic and metabolomic profiling reveals dysregulation of purine metabolism during the acute phase of spinal cord injury in rats
por: Zeng, Zhong, et al.
Publicado: (2022)

Transcriptomic and proteomic profiling of Na(V)1.8-expressing mouse nociceptors
por: Schmidt, Manuela, et al.
Publicado: (2022)

Upregulation of TRPM3 in nociceptors innervating inflamed tissue
por: Mulier, Marie, et al.
Publicado: (2020)

Drosophila mechanical nociceptors preferentially sense localized poking
por: Liu, Zhen, et al.
Publicado: (2022)

Comprehensive phenotyping of cutaneous afferents reveals early-onset alterations in nociceptor response properties, release of CGRP, and hindpaw edema following spinal cord injury
por: Eller, Olivia C., et al.
Publicado: (2022)

Inflammogenesis of Secondary Spinal Cord Injury
por: Anwar, M. Akhtar, et al.
Publicado: (2016)

Review of Epidural Spinal Cord Stimulation for Augmenting Cough after Spinal Cord Injury
por: Hachmann, Jan T., et al.
Publicado: (2017)

Spinal Cord Cells from Pre-metamorphic Stages Differentiate into Neurons and Promote Axon Growth and Regeneration after Transplantation into the Injured Spinal Cord of Non-regenerative Xenopus laevis Froglets
por: Méndez-Olivos, Emilio E., et al.
Publicado: (2017)

Preclinical evidence supporting the clinical development of central pattern generator-modulating therapies for chronic spinal cord-injured patients
por: Guertin, Pierre A.
Publicado: (2014)

Epidural combined optical and electrical stimulation induces high-specificity activation of target muscles in spinal cord injured rats
por: Guo, Xiao-Jun, et al.
Publicado: (2023)

Expansion Duroplasty Improves Intraspinal Pressure, Spinal Cord Perfusion Pressure, and Vascular Pressure Reactivity Index in Patients with Traumatic Spinal Cord Injury: Injured Spinal Cord Pressure Evaluation Study
por: Phang, Isaac, et al.
Publicado: (2015)

Region-Resolved Quantitative Proteome Profiling Reveals Molecular Dynamics Associated With Chronic Pain in the PNS and Spinal Cord
por: Barry, Allison M., et al.
Publicado: (2018)

Sexual rehabilitation of the spinal-cord-injured patient
Publicado: (1991)

Astrocyte transplantation for repairing the injured spinal cord
por: Zheng, Xiaolong, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_e5qpvqjkkn3e1q3lpa9l9s87e5