Assessment of an Antibody-in-Lymphocyte Supernatant Assay for the Etiological Diagnosis of Pneumococcal Pneumonia in Children

New diagnostic tests for the etiology of childhood pneumonia are needed. We evaluated the antibody-in-lymphocyte supernatant (ALS) assay to detect immunoglobulin (Ig) G secretion from ex vivo peripheral blood mononuclear cell (PBMC) culture, as a potential diagnostic test for pneumococcal pneumonia....

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Detalles Bibliográficos
Autores principales: Carter, Michael J., Gurung, Pallavi, Jones, Claire, Rajkarnikar, Shristy, Kandasamy, Rama, Gurung, Meeru, Thorson, Stephen, Gautam, Madhav C., Prajapati, Krishna G., Khadka, Bibek, Maharjan, Anju, Knight, Julian C., Murdoch, David R., Darton, Thomas C., Voysey, Merryn, Wahl, Brian, O'Brien, Katherine L., Kelly, Sarah, Ansari, Imran, Shah, Ganesh, Ekström, Nina, Melin, Merit, Pollard, Andrew J., Kelly, Dominic F., Shrestha, Shrijana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988833/
https://www.ncbi.nlm.nih.gov/pubmed/32039044
http://dx.doi.org/10.3389/fcimb.2019.00459

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