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Mitochondrial dysfunction generates a growth-restraining signal linked to pyruvate in Drosophila larvae
The Drosophila bang-sensitive mutant tko(25t), manifesting a global deficiency in oxidative phosphorylation due to a mitochondrial protein synthesis defect, exhibits a pronounced delay in larval development. We previously identified a number of metabolic abnormalities in tko(25t) larvae, including e...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988875/ https://www.ncbi.nlm.nih.gov/pubmed/31526131 http://dx.doi.org/10.1080/19336934.2019.1662266 |