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The long-noncoding RNA MALAT1 regulates TGF-β/Smad signaling through formation of a lncRNA-protein complex with Smads, SETD2 and PPM1A in hepatic cells

Recent studies have demonstrated the implication of long noncoding RNAs (lncRNAs) in a variety of physiological and pathological processes. However, the majority of lncRNAs are functionally unknown. The current study describes that the lncRNA MALAT1 regulates TGF-β/Smad signaling pathway through for...

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Detalles Bibliográficos
Autores principales: Zhang, Jinqiang, Han, Chang, Song, Kyoungsub, Chen, Weina, Ungerleider, Nathan, Yao, Lu, Ma, Wenbo, Wu, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988980/
https://www.ncbi.nlm.nih.gov/pubmed/31995604
http://dx.doi.org/10.1371/journal.pone.0228160