A CRISPR-Assisted Nonhomologous End-Joining Strategy for Efficient Genome Editing in Mycobacterium tuberculosis

New tools for genetic manipulation of Mycobacterium tuberculosis are needed for the development of new drug regimens and vaccines aimed at curing tuberculosis infections. Clustered regularly interspaced short palindromic repeat (CRISPR)–CRISPR-associated protein (Cas) systems generate a highly speci...

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Detalles Bibliográficos
Autores principales: Yan, Mei-Yi, Li, Si-Shang, Ding, Xin-Yuan, Guo, Xiao-Peng, Jin, Qi, Sun, Yi-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989103/
https://www.ncbi.nlm.nih.gov/pubmed/31992616
http://dx.doi.org/10.1128/mBio.02364-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989103/
https://www.ncbi.nlm.nih.gov/pubmed/31992616
http://dx.doi.org/10.1128/mBio.02364-19

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