Binding of Host Cell Surface Protein Disulfide Isomerase by Anaplasma phagocytophilum Asp14 Enables Pathogen Infection

Diverse intracellular pathogens rely on eukaryotic cell surface disulfide reductases to invade host cells. Pharmacologic inhibition of these enzymes is cytotoxic, making it impractical for treatment. Identifying and mechanistically dissecting microbial proteins that co-opt surface reductases could r...

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Detalles Bibliográficos
Autores principales: Green, Ryan S., Naimi, Waheeda A., Oliver, Lee D., O’Bier, Nathaniel, Cho, Jaehyung, Conrad, Daniel H., Martin, Rebecca K., Marconi, Richard T., Carlyon, Jason A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989111/
https://www.ncbi.nlm.nih.gov/pubmed/31992623
http://dx.doi.org/10.1128/mBio.03141-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989111/
https://www.ncbi.nlm.nih.gov/pubmed/31992623
http://dx.doi.org/10.1128/mBio.03141-19

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