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Poly(amino acids) as a potent self-adjuvanting delivery system for peptide-based nanovaccines

To be optimally effective, peptide-based vaccines need to be administered with adjuvants. Many currently available adjuvants are toxic, not biodegradable; they invariably invoke adverse reactions, including allergic responses and excessive inflammation. A nontoxic, biodegradable, biocompatible, self...

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Detalles Bibliográficos
Autores principales: Skwarczynski, Mariusz, Zhao, Guangzu, Boer, Jennifer C., Ozberk, Victoria, Azuar, Armira, Cruz, Jazmina Gonzalez, Giddam, Ashwini Kumar, Khalil, Zeinab G., Pandey, Manisha, Shibu, Mohini A., Hussein, Waleed M., Nevagi, Reshma J., Batzloff, Michael R., Wells, James W., Capon, Robert J., Plebanski, Magdalena, Good, Michael F., Toth, Istvan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989150/
https://www.ncbi.nlm.nih.gov/pubmed/32064333
http://dx.doi.org/10.1126/sciadv.aax2285