Highly Combinatorial Genetic Interaction Analysis Reveals a Multi-Drug Transporter Influence Network

Many traits are complex, depending non-additively on variant combinations. Even in model systems, such as the yeast S. cerevisiae, carrying out the high-order variant-combination testing needed to dissect complex traits remains a daunting challenge. Here, we describe “X-gene” genetic analysis (XGA),...

Descripción completa

Detalles Bibliográficos
Autores principales: Celaj, Albi, Gebbia, Marinella, Musa, Louai, Cote, Atina G., Snider, Jamie, Wong, Victoria, Ko, Minjeong, Fong, Tiffany, Bansal, Paul, Mellor, Joseph C., Seesankar, Gireesh, Nguyen, Maria, Zhou, Shijie, Wang, Liangxi, Kishore, Nishka, Stagljar, Igor, Suzuki, Yo, Yachie, Nozomu, Roth, Frederick P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989212/
https://www.ncbi.nlm.nih.gov/pubmed/31668799
http://dx.doi.org/10.1016/j.cels.2019.09.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989212/
https://www.ncbi.nlm.nih.gov/pubmed/31668799
http://dx.doi.org/10.1016/j.cels.2019.09.009

Ejemplares similares