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Development of a UPLC-MS/MS method for the therapeutic monitoring of L-asparaginase

This study aimed to develop a UPLC-MS/MS method for determining plasma levels of L-aspartic acid and L-asparagine and the activity of L-asparaginase. L-aspartic acid, L-asparagine, and L-aspartic acid-2,3,3-d(3) were extracted from human plasma by protein precipitation with sulfosalicylic acid (30%,...

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Detalles Bibliográficos
Autores principales:	Jeong, Hyeon-Cheol, Kim, Therasa, Yang, Deok-Hwan, Shin, Kwang-Hee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Clinical Pharmacology and Therapeutics 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989229/ https://www.ncbi.nlm.nih.gov/pubmed/32055563 http://dx.doi.org/10.12793/tcp.2018.26.3.134

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