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Mechanistic ligand-receptor interaction model: operational model of agonism

This tutorial explains the basic principles of mechanistic ligand-receptor interaction model, which is an operational model of agonism. A growing number of agonist drugs, especially immune oncology drugs, is currently being developed. In this tutorial, time-dependent ordinary differential equation f...

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Detalles Bibliográficos
Autores principales: Kim, Hyungsub, Lim, Hyeong-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Clinical Pharmacology and Therapeutics 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989234/
https://www.ncbi.nlm.nih.gov/pubmed/32055560
http://dx.doi.org/10.12793/tcp.2018.26.3.115