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Electrical storm induced by hypokalemia associated with herbal medicines containing licorice

A 60-year-old woman presented with polymorphic ventricular tachycardia secondary to hypokalemia, which necessitated dozens of DC cardioversions. She was not taking any other medication and denied any vomiting or diarrhea. Further investigation for hypokalemia suggested a hypermineralocorticoid state...

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Detalles Bibliográficos
Autores principales: Kim, Hyun Kuk, Kim, Sung Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Clinical Pharmacology and Therapeutics 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989247/
https://www.ncbi.nlm.nih.gov/pubmed/32055584
http://dx.doi.org/10.12793/tcp.2019.27.2.69
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author Kim, Hyun Kuk
Kim, Sung Soo
author_facet Kim, Hyun Kuk
Kim, Sung Soo
author_sort Kim, Hyun Kuk
collection PubMed
description A 60-year-old woman presented with polymorphic ventricular tachycardia secondary to hypokalemia, which necessitated dozens of DC cardioversions. She was not taking any other medication and denied any vomiting or diarrhea. Further investigation for hypokalemia suggested a hypermineralocorticoid state. Repeated inquiry prompted the patient to admit to taking herbal medicine containing licorice. She was treated with magnesium sulfate, potassium infusion, and intravenous lidocaine. A potassium-sparing diuretic was also prescribed. On the seventh day, the patient was discharged from the hospital with advice to discontinue taking herbal medicines containing licorice. She has been followed up at our outpatient clinic without further symptoms for 3 years. This case highlights the potential for cardiovascular complications associated with consumption of herbal medicines such as licorice. Clinicians should be aware that patients presenting to the emergency department with ventricular arrhythmia and uncertain hypokalemia should be questioned about licorice intake. Obtaining a detailed history from patients admitted to the hospital for electrical storm is essential.
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spelling pubmed-69892472020-02-13 Electrical storm induced by hypokalemia associated with herbal medicines containing licorice Kim, Hyun Kuk Kim, Sung Soo Transl Clin Pharmacol Case Report A 60-year-old woman presented with polymorphic ventricular tachycardia secondary to hypokalemia, which necessitated dozens of DC cardioversions. She was not taking any other medication and denied any vomiting or diarrhea. Further investigation for hypokalemia suggested a hypermineralocorticoid state. Repeated inquiry prompted the patient to admit to taking herbal medicine containing licorice. She was treated with magnesium sulfate, potassium infusion, and intravenous lidocaine. A potassium-sparing diuretic was also prescribed. On the seventh day, the patient was discharged from the hospital with advice to discontinue taking herbal medicines containing licorice. She has been followed up at our outpatient clinic without further symptoms for 3 years. This case highlights the potential for cardiovascular complications associated with consumption of herbal medicines such as licorice. Clinicians should be aware that patients presenting to the emergency department with ventricular arrhythmia and uncertain hypokalemia should be questioned about licorice intake. Obtaining a detailed history from patients admitted to the hospital for electrical storm is essential. Korean Society for Clinical Pharmacology and Therapeutics 2019-06 2019-06-28 /pmc/articles/PMC6989247/ /pubmed/32055584 http://dx.doi.org/10.12793/tcp.2019.27.2.69 Text en Copyright © 2019 Translational and Clinical Pharmacology http://creativecommons.org/licenses/by-nc/3.0/ It is identical to the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/).
spellingShingle Case Report
Kim, Hyun Kuk
Kim, Sung Soo
Electrical storm induced by hypokalemia associated with herbal medicines containing licorice
title Electrical storm induced by hypokalemia associated with herbal medicines containing licorice
title_full Electrical storm induced by hypokalemia associated with herbal medicines containing licorice
title_fullStr Electrical storm induced by hypokalemia associated with herbal medicines containing licorice
title_full_unstemmed Electrical storm induced by hypokalemia associated with herbal medicines containing licorice
title_short Electrical storm induced by hypokalemia associated with herbal medicines containing licorice
title_sort electrical storm induced by hypokalemia associated with herbal medicines containing licorice
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989247/
https://www.ncbi.nlm.nih.gov/pubmed/32055584
http://dx.doi.org/10.12793/tcp.2019.27.2.69
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