NRARP displays either pro- or anti-tumoral roles in T-cell acute lymphoblastic leukemia depending on Notch and Wnt signaling

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy with a dismal prognosis in patients with resistant or relapsed disease. Although NOTCH is a known driver in T-ALL, its clinical inhibition has significant limitations. Our previous studies suggested that NRARP, a n...

Descripción completa

Detalles Bibliográficos
Autores principales: Pinto, Inês, Duque, Mafalda, Gonçalves, Joana, Akkapeddi, Padma, Oliveira, Mariana L., Cabrita, Rita, Yunes, J. Andrés, Durum, Scott K., Barata, João T., Fragoso, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989401/
https://www.ncbi.nlm.nih.gov/pubmed/31586130
http://dx.doi.org/10.1038/s41388-019-1042-9

Ejemplares similares

Ejemplares similares