Cargando…

Left Amygdala Regulates the Cerebral Reading Network During Fast Emotion Word Processing

Emotion words constitute a special class of verbal stimuli which can quickly activate the limbic system outside the left-hemisphere language network. Such fast response to emotion words may arise independently of the left occipitotemporal area involved in visual word-form analysis and rely on a dist...

Descripción completa

Detalles Bibliográficos
Autores principales: Nakamura, Kimihiro, Inomata, Tomoe, Uno, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989437/
https://www.ncbi.nlm.nih.gov/pubmed/32038435
http://dx.doi.org/10.3389/fpsyg.2020.00001
_version_ 1783492398327791616
author Nakamura, Kimihiro
Inomata, Tomoe
Uno, Akira
author_facet Nakamura, Kimihiro
Inomata, Tomoe
Uno, Akira
author_sort Nakamura, Kimihiro
collection PubMed
description Emotion words constitute a special class of verbal stimuli which can quickly activate the limbic system outside the left-hemisphere language network. Such fast response to emotion words may arise independently of the left occipitotemporal area involved in visual word-form analysis and rely on a distinct amygdala-dependent emotion circuit involved in fearful face processing. Using a hemifield priming paradigm with fMRI, we explored how the left and right amygdala systems interact with the reading network during emotion word processing. On each trial, participants viewed a centrally presented target which was preceded by a masked prime flashed either to the left or right visual field. Primes and targets, each denoting negative or positive nouns, could be either affectively congruent or incongruent with each other. We observed that affective congruency produced parallel changes in neural priming between the left frontal and parietotemporal regions and the bilateral amygdala. However, we also found that the left, but not right, amygdala exhibited significant change in functional connectivity with the neural components of reading as a function of affective congruency. Collectively, these results suggest that emotion words activate the bilateral amygdala during early stages of emotion word processing, whereas only the left amygdala exerts a long-distance regulatory influence over the reading network via its strong within-hemisphere connectivity.
format Online
Article
Text
id pubmed-6989437
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-69894372020-02-07 Left Amygdala Regulates the Cerebral Reading Network During Fast Emotion Word Processing Nakamura, Kimihiro Inomata, Tomoe Uno, Akira Front Psychol Psychology Emotion words constitute a special class of verbal stimuli which can quickly activate the limbic system outside the left-hemisphere language network. Such fast response to emotion words may arise independently of the left occipitotemporal area involved in visual word-form analysis and rely on a distinct amygdala-dependent emotion circuit involved in fearful face processing. Using a hemifield priming paradigm with fMRI, we explored how the left and right amygdala systems interact with the reading network during emotion word processing. On each trial, participants viewed a centrally presented target which was preceded by a masked prime flashed either to the left or right visual field. Primes and targets, each denoting negative or positive nouns, could be either affectively congruent or incongruent with each other. We observed that affective congruency produced parallel changes in neural priming between the left frontal and parietotemporal regions and the bilateral amygdala. However, we also found that the left, but not right, amygdala exhibited significant change in functional connectivity with the neural components of reading as a function of affective congruency. Collectively, these results suggest that emotion words activate the bilateral amygdala during early stages of emotion word processing, whereas only the left amygdala exerts a long-distance regulatory influence over the reading network via its strong within-hemisphere connectivity. Frontiers Media S.A. 2020-01-23 /pmc/articles/PMC6989437/ /pubmed/32038435 http://dx.doi.org/10.3389/fpsyg.2020.00001 Text en Copyright © 2020 Nakamura, Inomata and Uno. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Psychology
Nakamura, Kimihiro
Inomata, Tomoe
Uno, Akira
Left Amygdala Regulates the Cerebral Reading Network During Fast Emotion Word Processing
title Left Amygdala Regulates the Cerebral Reading Network During Fast Emotion Word Processing
title_full Left Amygdala Regulates the Cerebral Reading Network During Fast Emotion Word Processing
title_fullStr Left Amygdala Regulates the Cerebral Reading Network During Fast Emotion Word Processing
title_full_unstemmed Left Amygdala Regulates the Cerebral Reading Network During Fast Emotion Word Processing
title_short Left Amygdala Regulates the Cerebral Reading Network During Fast Emotion Word Processing
title_sort left amygdala regulates the cerebral reading network during fast emotion word processing
topic Psychology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989437/
https://www.ncbi.nlm.nih.gov/pubmed/32038435
http://dx.doi.org/10.3389/fpsyg.2020.00001
work_keys_str_mv AT nakamurakimihiro leftamygdalaregulatesthecerebralreadingnetworkduringfastemotionwordprocessing
AT inomatatomoe leftamygdalaregulatesthecerebralreadingnetworkduringfastemotionwordprocessing
AT unoakira leftamygdalaregulatesthecerebralreadingnetworkduringfastemotionwordprocessing