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Insulin-independent stimulation of skeletal muscle glucose uptake by low-dose abscisic acid via AMPK activation
Abscisic acid (ABA) is a plant hormone active also in mammals where it regulates, at nanomolar concentrations, blood glucose homeostasis. Here we investigated the mechanism through which low-dose ABA controls glycemia and glucose fate. ABA stimulated uptake of the fluorescent glucose analog 2-NBDG b...
Autores principales: | Magnone, Mirko, Emionite, Laura, Guida, Lucrezia, Vigliarolo, Tiziana, Sturla, Laura, Spinelli, Sonia, Buschiazzo, Ambra, Marini, Cecilia, Sambuceti, Gianmario, De Flora, Antonio, Orengo, Anna Maria, Cossu, Vanessa, Ferrando, Sara, Barbieri, Ottavia, Zocchi, Elena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989460/ https://www.ncbi.nlm.nih.gov/pubmed/31996711 http://dx.doi.org/10.1038/s41598-020-58206-0 |
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