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Comprehensive Analysis of Copy Number Variations in Kidney Cancer by Single-Cell Exome Sequencing

Clear-cell renal cell carcinoma (ccRCC) is the most common and lethal subtype of kidney cancer. VHL and PBRM1 are the top two significantly mutated genes in ccRCC specimens, while the genetic mechanism of the VHL/PBRM1-negative ccRCC remains to be elucidated. Here we carried out a comprehensive anal...

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Detalles Bibliográficos
Autores principales: Zhou, Wenyang, Yang, Fan, Xu, Zhaochun, Luo, Meng, Wang, Pingping, Guo, Yu, Nie, Huan, Yao, Lifen, Jiang, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989475/
https://www.ncbi.nlm.nih.gov/pubmed/32038722
http://dx.doi.org/10.3389/fgene.2019.01379

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