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Hepatitis E Virus Cysteine Protease Has Papain Like Properties Validated by in silico Modeling and Cell-Free Inhibition Assays

Hepatitis E virus (HEV) has emerged as a global health concern during the last decade. In spite of a high mortality rate in pregnant women with fulminant hepatitis, no antiviral drugs or licensed vaccine is available in India. HEV-protease is a pivotal enzyme responsible for ORF1 polyprotein process...

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Detalles Bibliográficos
Autores principales:	Saraswat, Shweta, Chaudhary, Meenakshi, Sehgal, Deepak
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989534/ https://www.ncbi.nlm.nih.gov/pubmed/32039053 http://dx.doi.org/10.3389/fcimb.2019.00478

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