Cargando…

Spatiotemporal contact between peroxisomes and lipid droplets regulates fasting-induced lipolysis via PEX5

Lipid droplets (LDs) are key subcellular organelles for regulating lipid metabolism. Although several subcellular organelles participate in lipid metabolism, it remains elusive whether physical contacts between subcellular organelles and LDs might be involved in lipolysis upon nutritional deprivatio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kong, Jinuk, Ji, Yul, Jeon, Yong Geun, Han, Ji Seul, Han, Kyung Hee, Lee, Jung Hyun, Lee, Gung, Jang, Hagoon, Choe, Sung Sik, Baes, Myriam, Kim, Jae Bum
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989686/ https://www.ncbi.nlm.nih.gov/pubmed/31996685 http://dx.doi.org/10.1038/s41467-019-14176-0

Ejemplares similares

Unbalanced lipolysis results in lipotoxicity and mitochondrial damage in peroxisome-deficient Pex19 mutants
por: Bülow, Margret H., et al.
Publicado: (2018)

Feeding Period Restriction Alters the Expression of Peripheral Circadian Rhythm Genes without Changing Body Weight in Mice
por: Jang, Hagoon, et al.
Publicado: (2012)

PEX13 prevents pexophagy by regulating ubiquitinated PEX5 and peroxisomal ROS
por: Demers, Nicholas D., et al.
Publicado: (2023)

Membrane Interactions of the Peroxisomal Proteins PEX5 and PEX14
por: Gaussmann, Stefan, et al.
Publicado: (2021)

PEX11 promotes peroxisome division independently of peroxisome metabolism
por: Li, Xiaoling, et al.
Publicado: (2002)

The peroxin Pex34p functions with the Pex11 family of peroxisomal divisional proteins to regulate the peroxisome population in yeast
por: Tower, Robert J., et al.
Publicado: (2011)

Peroxisomal protein PEX13 functions in selective autophagy
por: Lee, Ming Y, et al.
Publicado: (2016)

The peroxisomal membrane protein import receptor Pex3p is directly transported to peroxisomes by a novel Pex19p- and Pex16p-dependent pathway
por: Matsuzaki, Takashi, et al.
Publicado: (2008)

PEX16 contributes to peroxisome maintenance by constantly trafficking PEX3 via the ER
por: Aranovich, Alexander, et al.
Publicado: (2014)

The peroxisomal AAA-ATPase Pex1/Pex6 unfolds substrates by processive threading
por: Gardner, Brooke M., et al.
Publicado: (2018)

Insights into the Structure and Function of the Pex1/Pex6 AAA-ATPase in Peroxisome Homeostasis
por: Judy, Ryan M., et al.
Publicado: (2022)

Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate
por: Rüttermann, Maximilian, et al.
Publicado: (2023)

Pex12 Interacts with Pex5 and Pex10 and Acts Downstream of Receptor Docking in Peroxisomal Matrix Protein Import
por: Chang, Chia-Che, et al.
Publicado: (1999)

Involvement of Pex13p in Pex14p Localization and Peroxisomal Targeting Signal 2–dependent Protein Import into Peroxisomes
por: Girzalsky, Wolfgang, et al.
Publicado: (1999)

Interdependence of the Peroxisome-targeting Receptors in Arabidopsis thaliana: PEX7 Facilitates PEX5 Accumulation and Import of PTS1 Cargo into Peroxisomes
por: Ramón, Naxhiely Martínez, et al.
Publicado: (2010)

Structure–function analysis of the ER-peroxisome contact site protein Pex32
por: Wu, Fei, et al.
Publicado: (2022)

Heimler Syndrome Is Caused by Hypomorphic Mutations in the Peroxisome-Biogenesis Genes PEX1 and PEX6
por: Ratbi, Ilham, et al.
Publicado: (2015)

The Structure of the Arabidopsis PEX4-PEX22 Peroxin Complex—Insights Into Ubiquitination at the Peroxisomal Membrane
por: Traver, Melissa S., et al.
Publicado: (2022)

PEX16: a multifaceted regulator of peroxisome biogenesis
por: Kim, Peter K., et al.
Publicado: (2013)

PEX5 and Ubiquitin Dynamics on Mammalian Peroxisome Membranes
por: Brown, Aidan I., et al.
Publicado: (2014)

Knockdown of PEX16 Induces Autophagic Degradation of Peroxisomes
por: Wei, Xiaofan, et al.
Publicado: (2021)

Peroxisomal Disorders and Their Mouse Models Point to Essential Roles of Peroxisomes for Retinal Integrity
por: Das, Yannick, et al.
Publicado: (2021)

De Novo Peroxisome Biogenesis in Penicillium Chrysogenum Is Not Dependent on the Pex11 Family Members or Pex16
por: Opaliński, Łukasz, et al.
Publicado: (2012)

Recognition and Chaperoning by Pex19, Followed by Trafficking and Membrane Insertion of the Peroxisome Proliferation Protein, Pex11
por: Zientara-Rytter, Katarzyna M., et al.
Publicado: (2022)

Pex22p of Pichia pastoris, Essential for Peroxisomal Matrix Protein Import, Anchors the Ubiquitin-Conjugating Enzyme, Pex4p, on the Peroxisomal Membrane
por: Koller, Antonius, et al.
Publicado: (1999)

Pex13 and Pex14, the key components of the peroxisomal docking complex, are required for peroxisome formation, host infection and pathogenicity-related morphogenesis in Magnaporthe oryzae
por: Wang, Jiao-Yu, et al.
Publicado: (2019)

PEX3 functions as a PEX19 docking factor in the import of class I peroxisomal membrane proteins
por: Fang, Yi, et al.
Publicado: (2004)

Peroxisomal Membrane Fusion Requires Two Aaa Family Atpases, Pex1p and Pex6p
por: Titorenko, Vladimir I., et al.
Publicado: (2000)

Yeast pex1 cells contain peroxisomal ghosts that import matrix proteins upon reintroduction of Pex1
por: Knoops, Kèvin, et al.
Publicado: (2015)

A Mechanistic Perspective on PEX1 and PEX6, Two AAA+ Proteins of the Peroxisomal Protein Import Machinery
por: Pedrosa, Ana G., et al.
Publicado: (2019)

Pex7p translocates in and out of peroxisomes in Saccharomyces cerevisiae
por: Nair, Devi M., et al.
Publicado: (2004)

Membrane curvature during peroxisome fission requires Pex11
por: Opaliński, Łukasz, et al.
Publicado: (2011)

Pex3 peroxisome biogenesis proteins function in peroxisome inheritance as class V myosin receptors
por: Chang, Jinlan, et al.
Publicado: (2009)

Allosteric modulation of peroxisomal membrane protein recognition by farnesylation of the peroxisomal import receptor PEX19
por: Emmanouilidis, Leonidas, et al.
Publicado: (2017)

Characterization of two common 5' polymorphisms in PEX1 and correlation to survival in PEX1 peroxisome biogenesis disorder patients
por: Thoms, Sven, et al.
Publicado: (2011)

Peroxisome deficient invertebrate and vertebrate animal models
por: Van Veldhoven, Paul P., et al.
Publicado: (2013)

Pex19 Binds Multiple Peroxisomal Membrane Proteins, Is Predominantly Cytoplasmic, and Is Required for Peroxisome Membrane Synthesis
por: Sacksteder, Katherine A., et al.
Publicado: (2000)

Peroxisome reintroduction in Hansenula polymorpha requires Pex25 and Rho1
por: Saraya, Ruchi, et al.
Publicado: (2011)

A dual function for Pex3p in peroxisome formation and inheritance
por: Munck, Joanne M., et al.
Publicado: (2009)

Pex11mediates peroxisomal proliferation by promoting deformation of the lipid membrane
por: Yoshida, Yumi, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_u3n4a7lneqckpcvd7e98lkdr6r