Single-cell transcriptomics identifies CD44 as a marker and regulator of endothelial to haematopoietic transition

The endothelial to haematopoietic transition (EHT) is the process whereby haemogenic endothelium differentiates into haematopoietic stem and progenitor cells (HSPCs). The intermediary steps of this process are unclear, in particular the identity of endothelial cells that give rise to HSPCs is unknow...

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Detalles Bibliográficos
Autores principales: Oatley, Morgan, Bölükbası, Özge Vargel, Svensson, Valentine, Shvartsman, Maya, Ganter, Kerstin, Zirngibl, Katharina, Pavlovich, Polina V., Milchevskaya, Vladislava, Foteva, Vladimira, Natarajan, Kedar N., Baying, Bianka, Benes, Vladimir, Patil, Kiran R., Teichmann, Sarah A., Lancrin, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989687/
https://www.ncbi.nlm.nih.gov/pubmed/31996681
http://dx.doi.org/10.1038/s41467-019-14171-5

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