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Intrinsic connectivity networks from childhood to late adolescence: Effects of age and sex

There is limited evidence on the effects of age and sex on intrinsic connectivity of networks underlying cognition during childhood and adolescence. Independent component analysis was conducted in 113 subjects aged 7–18; the default mode, executive control, anterior salience, basal ganglia, language...

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Autores principales: Solé-Padullés, Cristina, Castro-Fornieles, Josefina, de la Serna, Elena, Calvo, Rosa, Baeza, Inmaculada, Moya, Jaime, Lázaro, Luisa, Rosa, Mireia, Bargalló, Nuria, Sugranyes, Gisela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990074/
https://www.ncbi.nlm.nih.gov/pubmed/26657414
http://dx.doi.org/10.1016/j.dcn.2015.11.004
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author Solé-Padullés, Cristina
Castro-Fornieles, Josefina
de la Serna, Elena
Calvo, Rosa
Baeza, Inmaculada
Moya, Jaime
Lázaro, Luisa
Rosa, Mireia
Bargalló, Nuria
Sugranyes, Gisela
author_facet Solé-Padullés, Cristina
Castro-Fornieles, Josefina
de la Serna, Elena
Calvo, Rosa
Baeza, Inmaculada
Moya, Jaime
Lázaro, Luisa
Rosa, Mireia
Bargalló, Nuria
Sugranyes, Gisela
author_sort Solé-Padullés, Cristina
collection PubMed
description There is limited evidence on the effects of age and sex on intrinsic connectivity of networks underlying cognition during childhood and adolescence. Independent component analysis was conducted in 113 subjects aged 7–18; the default mode, executive control, anterior salience, basal ganglia, language and visuospatial networks were identified. The effect of age was examined with multiple regression, while sex and ‘age × sex’ interactions were assessed by dividing the sample according to age (7–12 and 13–18 years). As age increased, connectivity in the dorsal and ventral default mode network became more anterior and posterior, respectively, while in the executive control network, connectivity increased within frontoparietal regions. The basal ganglia network showed increased engagement of striatum, thalami and precuneus. The anterior salience network showed greater connectivity in frontal areas and anterior cingulate, and less connectivity of orbitofrontal, middle cingulate and temporoparietal regions. The language network presented increased connectivity of inferior frontal and decreased connectivity within the right middle frontal and left inferior parietal cortices. The visuospatial network showed greater engagement of inferior parietal and frontal cortices. No effect of sex, nor age by sex interactions was observed. These findings provide evidence of strengthening of cortico-cortical and cortico-subcortical networks across childhood and adolescence.
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spelling pubmed-69900742020-02-03 Intrinsic connectivity networks from childhood to late adolescence: Effects of age and sex Solé-Padullés, Cristina Castro-Fornieles, Josefina de la Serna, Elena Calvo, Rosa Baeza, Inmaculada Moya, Jaime Lázaro, Luisa Rosa, Mireia Bargalló, Nuria Sugranyes, Gisela Dev Cogn Neurosci Original Research There is limited evidence on the effects of age and sex on intrinsic connectivity of networks underlying cognition during childhood and adolescence. Independent component analysis was conducted in 113 subjects aged 7–18; the default mode, executive control, anterior salience, basal ganglia, language and visuospatial networks were identified. The effect of age was examined with multiple regression, while sex and ‘age × sex’ interactions were assessed by dividing the sample according to age (7–12 and 13–18 years). As age increased, connectivity in the dorsal and ventral default mode network became more anterior and posterior, respectively, while in the executive control network, connectivity increased within frontoparietal regions. The basal ganglia network showed increased engagement of striatum, thalami and precuneus. The anterior salience network showed greater connectivity in frontal areas and anterior cingulate, and less connectivity of orbitofrontal, middle cingulate and temporoparietal regions. The language network presented increased connectivity of inferior frontal and decreased connectivity within the right middle frontal and left inferior parietal cortices. The visuospatial network showed greater engagement of inferior parietal and frontal cortices. No effect of sex, nor age by sex interactions was observed. These findings provide evidence of strengthening of cortico-cortical and cortico-subcortical networks across childhood and adolescence. Elsevier 2015-11-25 /pmc/articles/PMC6990074/ /pubmed/26657414 http://dx.doi.org/10.1016/j.dcn.2015.11.004 Text en © 2015 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Research
Solé-Padullés, Cristina
Castro-Fornieles, Josefina
de la Serna, Elena
Calvo, Rosa
Baeza, Inmaculada
Moya, Jaime
Lázaro, Luisa
Rosa, Mireia
Bargalló, Nuria
Sugranyes, Gisela
Intrinsic connectivity networks from childhood to late adolescence: Effects of age and sex
title Intrinsic connectivity networks from childhood to late adolescence: Effects of age and sex
title_full Intrinsic connectivity networks from childhood to late adolescence: Effects of age and sex
title_fullStr Intrinsic connectivity networks from childhood to late adolescence: Effects of age and sex
title_full_unstemmed Intrinsic connectivity networks from childhood to late adolescence: Effects of age and sex
title_short Intrinsic connectivity networks from childhood to late adolescence: Effects of age and sex
title_sort intrinsic connectivity networks from childhood to late adolescence: effects of age and sex
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990074/
https://www.ncbi.nlm.nih.gov/pubmed/26657414
http://dx.doi.org/10.1016/j.dcn.2015.11.004
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