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Risk Factors of Anesthesia-Related Mortality and Morbidity in One Equine Hospital: A Retrospective Study on 1,161 Cases Undergoing Elective or Emergency Surgeries

A retrospective analysis was performed to determine mortality and morbidity rates for elective and emergency cases in an equine university teaching hospital. It investigated the effect of horse-, anesthetic-, timing, and clinician experience-related variables on anesthetic complications. In total, 1...

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Autores principales: Laurenza, Chiara, Ansart, Lèa, Portier, Karine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990105/
https://www.ncbi.nlm.nih.gov/pubmed/32039253
http://dx.doi.org/10.3389/fvets.2019.00514
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author Laurenza, Chiara
Ansart, Lèa
Portier, Karine
author_facet Laurenza, Chiara
Ansart, Lèa
Portier, Karine
author_sort Laurenza, Chiara
collection PubMed
description A retrospective analysis was performed to determine mortality and morbidity rates for elective and emergency cases in an equine university teaching hospital. It investigated the effect of horse-, anesthetic-, timing, and clinician experience-related variables on anesthetic complications. In total, 1,161 horses undergoing general anesthesia between January 2012 and December 2016 were included in the study. Patient information and details of the anesthetic, recovery period and immediate complications were retrieved from an archival database. Statistical analysis of qualitative and quantitative factors affecting anesthetic complications was performed using an univariable and multivariable ordinal logistic regression. Odds ratio of variables primarily affecting mortality and complications were calculated. Statistical significance was set at p < 0.05. General anesthesia-related global mortality rate was 1.4% (95% CI [7.1–10.4]) but was only 0.96% (95% CI [0.44–1.82]) for non-colic cases. The complication rate was 17.5% (n = 204; 95% CI [15.2–20.0]) of which 46.9% [39.4–54.5] were neuromuscular, 22.6% [16.7–29.5] were respiratory, 15.8% [10.8–22.0] were systemic, 13.6% [8.9–19.5] were cardiovascular, 1.1% [0.1–4.0] were other complications. Ninety two percent of complications occurred during recovery. Major risk factors for mortality and complications included high weight, surgeon experience, increasing age, high ASA score, long duration of anesthesia, quality of induction, lateral recumbency, orthopedic surgery, and hypotension. In these models, colic surgery did not influence the rate of any complications.
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spelling pubmed-69901052020-02-07 Risk Factors of Anesthesia-Related Mortality and Morbidity in One Equine Hospital: A Retrospective Study on 1,161 Cases Undergoing Elective or Emergency Surgeries Laurenza, Chiara Ansart, Lèa Portier, Karine Front Vet Sci Veterinary Science A retrospective analysis was performed to determine mortality and morbidity rates for elective and emergency cases in an equine university teaching hospital. It investigated the effect of horse-, anesthetic-, timing, and clinician experience-related variables on anesthetic complications. In total, 1,161 horses undergoing general anesthesia between January 2012 and December 2016 were included in the study. Patient information and details of the anesthetic, recovery period and immediate complications were retrieved from an archival database. Statistical analysis of qualitative and quantitative factors affecting anesthetic complications was performed using an univariable and multivariable ordinal logistic regression. Odds ratio of variables primarily affecting mortality and complications were calculated. Statistical significance was set at p < 0.05. General anesthesia-related global mortality rate was 1.4% (95% CI [7.1–10.4]) but was only 0.96% (95% CI [0.44–1.82]) for non-colic cases. The complication rate was 17.5% (n = 204; 95% CI [15.2–20.0]) of which 46.9% [39.4–54.5] were neuromuscular, 22.6% [16.7–29.5] were respiratory, 15.8% [10.8–22.0] were systemic, 13.6% [8.9–19.5] were cardiovascular, 1.1% [0.1–4.0] were other complications. Ninety two percent of complications occurred during recovery. Major risk factors for mortality and complications included high weight, surgeon experience, increasing age, high ASA score, long duration of anesthesia, quality of induction, lateral recumbency, orthopedic surgery, and hypotension. In these models, colic surgery did not influence the rate of any complications. Frontiers Media S.A. 2020-01-22 /pmc/articles/PMC6990105/ /pubmed/32039253 http://dx.doi.org/10.3389/fvets.2019.00514 Text en Copyright © 2020 Laurenza, Ansart and Portier. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Veterinary Science
Laurenza, Chiara
Ansart, Lèa
Portier, Karine
Risk Factors of Anesthesia-Related Mortality and Morbidity in One Equine Hospital: A Retrospective Study on 1,161 Cases Undergoing Elective or Emergency Surgeries
title Risk Factors of Anesthesia-Related Mortality and Morbidity in One Equine Hospital: A Retrospective Study on 1,161 Cases Undergoing Elective or Emergency Surgeries
title_full Risk Factors of Anesthesia-Related Mortality and Morbidity in One Equine Hospital: A Retrospective Study on 1,161 Cases Undergoing Elective or Emergency Surgeries
title_fullStr Risk Factors of Anesthesia-Related Mortality and Morbidity in One Equine Hospital: A Retrospective Study on 1,161 Cases Undergoing Elective or Emergency Surgeries
title_full_unstemmed Risk Factors of Anesthesia-Related Mortality and Morbidity in One Equine Hospital: A Retrospective Study on 1,161 Cases Undergoing Elective or Emergency Surgeries
title_short Risk Factors of Anesthesia-Related Mortality and Morbidity in One Equine Hospital: A Retrospective Study on 1,161 Cases Undergoing Elective or Emergency Surgeries
title_sort risk factors of anesthesia-related mortality and morbidity in one equine hospital: a retrospective study on 1,161 cases undergoing elective or emergency surgeries
topic Veterinary Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990105/
https://www.ncbi.nlm.nih.gov/pubmed/32039253
http://dx.doi.org/10.3389/fvets.2019.00514
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