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CRISPR-Cas Systems and the Paradox of Self-Targeting Spacers

CRISPR-Cas immune systems in bacteria and archaea record prior infections as spacers within each system’s CRISPR arrays. Spacers are normally derived from invasive genetic material and direct the immune system to complementary targets as part of future infections. However, not all spacers appear to...

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Detalles Bibliográficos
Autores principales: Wimmer, Franziska, Beisel, Chase L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990116/
https://www.ncbi.nlm.nih.gov/pubmed/32038537
http://dx.doi.org/10.3389/fmicb.2019.03078

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