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Required G(K1) to Suppress Automaticity of iPSC-CMs Depends Strongly on I(K1) Model Structure
Human-induced pluripotent stem cells derived cardiomyocytes (hiPSC-CMs) are a virtually endless source of human cardiomyocytes that may become a great tool for safety pharmacology; however, their electrical phenotype is immature: they show spontaneous action potentials (APs) and an unstable and depo...
Autores principales: | Fabbri, Alan, Goversen, Birgit, Vos, Marc A., van Veen, Toon A.B., de Boer, Teun P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990378/ https://www.ncbi.nlm.nih.gov/pubmed/31623886 http://dx.doi.org/10.1016/j.bpj.2019.08.040 |
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