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Arrhythmogenic Current Generation by Myofilament-Triggered Ca(2+) Release and Sarcomere Heterogeneity
Heterogeneous mechanical dyskinesis has been implicated in many arrhythmogenic phenotypes. Strain-dependent perturbations to cardiomyocyte electrophysiology may contribute to this arrhythmogenesis through processes referred to as mechanoelectric feedback. Although the role of stretch-activated ion c...
Autores principales: | Timmermann, Viviane, Edwards, Andrew G., Wall, Samuel T., Sundnes, Joakim, McCulloch, Andrew D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990379/ https://www.ncbi.nlm.nih.gov/pubmed/31810659 http://dx.doi.org/10.1016/j.bpj.2019.11.009 |
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