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N-Terminal Ubiquitination of Amyloidogenic Proteins Triggers Removal of Their Oligomers by the Proteasome Holoenzyme

Aggregation of amyloidogenic proteins is an abnormal biological process implicated in neurodegenerative disorders. Whereas the aggregation process of amyloid-forming proteins has been studied extensively, the mechanism of aggregate removal is poorly understood. We recently demonstrated that proteaso...

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Detalles Bibliográficos
Autores principales:	Ye, Yu, Klenerman, David, Finley, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990400/ https://www.ncbi.nlm.nih.gov/pubmed/31518613 http://dx.doi.org/10.1016/j.jmb.2019.08.021

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