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Novel Sulfonanilide Inhibitors of SHIP2 Enhance Glucose Uptake into Cultured Myotubes
[Image: see text] A series of substituted sulfonanilide analogs were prepared and evaluated as novel potent inhibitors of SH2 domain-containing inositol polyphosphate 5′-phosphatase 2 (SHIP2). SHIP2 has been shown to be a new attractive target for the treatment of insulin resistance in type 2 diabet...
Autores principales: | Berg, Mika E. A., Naams, Jette-Britt, Hautala, Laura C., Tolvanen, Tuomas A., Ahonen, Jari P., Lehtonen, Sanna, Wähälä, Kristiina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990439/ https://www.ncbi.nlm.nih.gov/pubmed/32010815 http://dx.doi.org/10.1021/acsomega.9b02944 |
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