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Synthetic Abortive HIV-1 RNAs Induce Potent Antiviral Immunity

Strong innate and adaptive immune responses are paramount in combating viral infections. Dendritic cells (DCs) detect viral infections via cytosolic RIG-I like receptors (RLRs) RIG-I and MDA5 leading to MAVS-induced immunity. The DEAD-box RNA helicase DDX3 senses abortive human immunodeficiency viru...

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Detalles Bibliográficos
Autores principales:	Stunnenberg, Melissa, Sprokholt, Joris K., van Hamme, John L., Kaptein, Tanja M., Zijlstra-Willems, Esther M., Gringhuis, Sonja I., Geijtenbeek, Teunis B. H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990453/ https://www.ncbi.nlm.nih.gov/pubmed/32038656 http://dx.doi.org/10.3389/fimmu.2020.00008

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