Pattern of nucleotide variants of TP53 and their correlation with the expression of p53 and its downstream proteins in a Sri Lankan cohort of breast and colorectal cancer patients

BACKGROUND: Breast cancer (BC) is known to be the most common malignancy in females whereas colorectal cancer (CRC) incidence also higher in both genders in Sri Lanka. TP53 is an important tumour suppressor gene and its somatic mutations are reported in approximately 27% of BC and 43% of CRC cases....

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Detalles Bibliográficos
Autores principales: Manoharan, Vahinipriya, Karunanayake, Eric Hamilton, Tennekoon, Kamani Hemamala, De Silva, Sumadee, Imthikab, Ahamed Ilyas Ahamed, De Silva, Kanishka, Angunawela, Preethika, Vishwakula, Sameera, Lunec, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990524/
https://www.ncbi.nlm.nih.gov/pubmed/32000721
http://dx.doi.org/10.1186/s12885-020-6573-5

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