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Silencing of microRNA-517a induces oxidative stress injury in melanoma cells via inactivation of the JNK signaling pathway by upregulating CDKN1C

BACKGROUND: Melanoma is notoriously resistant to current treatments, and less than 25% of metastatic melanoma cases respond to existing therapies. Growing evidence has shown that microRNAs (miRNAs) play a vital role in the prognosis of melanoma. MiR-517a has been implicated in many types of cancer;...

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Detalles Bibliográficos
Autores principales: Yang, Chao, Yan, Zeqiang, Hu, Fen, Wei, Wei, Sun, Zhihua, Xu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990552/
https://www.ncbi.nlm.nih.gov/pubmed/32015692
http://dx.doi.org/10.1186/s12935-019-1064-y