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Oleic acid ameliorates palmitic acid induced hepatocellular lipotoxicity by inhibition of ER stress and pyroptosis

BACKGROUND: Pyroptosis is a novel programmed cell death. It is identified as caspase-1 dependent and characterized by plasma-membrane rupture and release of proinflammatory intracellular contents inculuding IL-1 beta and IL-18. Pyroptosis is distinct from other forms of cell death, especially apopto...

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Detalles Bibliográficos
Autores principales: Zeng, Xin, Zhu, Min, Liu, Xiaohong, Chen, Xuanmin, Yuan, Yujia, Li, Lan, Liu, Jingping, Lu, Yanrong, Cheng, Jingqiu, Chen, Younan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990600/
https://www.ncbi.nlm.nih.gov/pubmed/32021639
http://dx.doi.org/10.1186/s12986-020-0434-8