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Neonatal ketamine exposure-induced hippocampal neuroapoptosis in the developing brain impairs adult spatial learning ability

Ketamine exposure can lead to selective neuroapoptosis in the developing brain. p(66)ShcA, the cellular adapter protein expressed selectively in immature neurons, is a known pro-apoptotic molecule that triggers neuroapoptosis when activated. Sprague-Dawley rats at postnatal day 7 were subcutaneously...

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Detalles Bibliográficos
Autores principales:	Lyu, Dan, Tang, Ning, Womack, Andrew W., He, Yong-Jin, Lin, Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer - Medknow 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990767/ https://www.ncbi.nlm.nih.gov/pubmed/31719253 http://dx.doi.org/10.4103/1673-5374.268929

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