Neuronal and peripheral damages induced by synthetic psychoactive substances: an update of recent findings from human and animal studies

Preclinical and clinical studies indicate that synthetic psychoactive substances, in addition to having abuse potential, may elicit toxic effects of varying severity at the peripheral and central levels. Nowadays, toxicity induced by synthetic psychoactive substances poses a serious harm for health,...

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Detalles Bibliográficos
Autores principales: Costa, Giulia, De Luca, Maria Antonietta, Piras, Gessica, Marongiu, Jacopo, Fattore, Liana, Simola, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990793/
https://www.ncbi.nlm.nih.gov/pubmed/31719240
http://dx.doi.org/10.4103/1673-5374.268895
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author Costa, Giulia
De Luca, Maria Antonietta
Piras, Gessica
Marongiu, Jacopo
Fattore, Liana
Simola, Nicola
author_facet Costa, Giulia
De Luca, Maria Antonietta
Piras, Gessica
Marongiu, Jacopo
Fattore, Liana
Simola, Nicola
author_sort Costa, Giulia
collection PubMed
description Preclinical and clinical studies indicate that synthetic psychoactive substances, in addition to having abuse potential, may elicit toxic effects of varying severity at the peripheral and central levels. Nowadays, toxicity induced by synthetic psychoactive substances poses a serious harm for health, since recreational use of these substances is on the rise among young and adult people. The present review summarizes recent findings on the peripheral and central toxicity elicited by “old” and “new” synthetic psychoactive substances in humans and experimental animals, focusing on amphetamine derivatives, hallucinogen and dissociative drugs and synthetic cannabinoids.
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spelling pubmed-69907932020-02-10 Neuronal and peripheral damages induced by synthetic psychoactive substances: an update of recent findings from human and animal studies Costa, Giulia De Luca, Maria Antonietta Piras, Gessica Marongiu, Jacopo Fattore, Liana Simola, Nicola Neural Regen Res Review Preclinical and clinical studies indicate that synthetic psychoactive substances, in addition to having abuse potential, may elicit toxic effects of varying severity at the peripheral and central levels. Nowadays, toxicity induced by synthetic psychoactive substances poses a serious harm for health, since recreational use of these substances is on the rise among young and adult people. The present review summarizes recent findings on the peripheral and central toxicity elicited by “old” and “new” synthetic psychoactive substances in humans and experimental animals, focusing on amphetamine derivatives, hallucinogen and dissociative drugs and synthetic cannabinoids. Wolters Kluwer - Medknow 2019-11-08 /pmc/articles/PMC6990793/ /pubmed/31719240 http://dx.doi.org/10.4103/1673-5374.268895 Text en Copyright: © Neural Regeneration Research http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Review
Costa, Giulia
De Luca, Maria Antonietta
Piras, Gessica
Marongiu, Jacopo
Fattore, Liana
Simola, Nicola
Neuronal and peripheral damages induced by synthetic psychoactive substances: an update of recent findings from human and animal studies
title Neuronal and peripheral damages induced by synthetic psychoactive substances: an update of recent findings from human and animal studies
title_full Neuronal and peripheral damages induced by synthetic psychoactive substances: an update of recent findings from human and animal studies
title_fullStr Neuronal and peripheral damages induced by synthetic psychoactive substances: an update of recent findings from human and animal studies
title_full_unstemmed Neuronal and peripheral damages induced by synthetic psychoactive substances: an update of recent findings from human and animal studies
title_short Neuronal and peripheral damages induced by synthetic psychoactive substances: an update of recent findings from human and animal studies
title_sort neuronal and peripheral damages induced by synthetic psychoactive substances: an update of recent findings from human and animal studies
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990793/
https://www.ncbi.nlm.nih.gov/pubmed/31719240
http://dx.doi.org/10.4103/1673-5374.268895
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