m(6)A facilitates YTHDF‐independent phase separation

N6‐methyladenosine (m(6)A) is one of the most abundant messenger RNA (mRNA) modifications in eukaryotes and is involved in various key processes of RNA metabolism. In this issue of Nature, Ries et al (2019) described the fundamental features of m6A modification of mRNAs in regulating the composition...

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Detalles Bibliográficos
Autores principales: Liu, Si‐Yu, Feng, Yi, Wu, Jun-Jie, Zou, Ming-Li, Sun, Zi-Li, Li, Xia, Yuan, Feng‐Lai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6991661/
https://www.ncbi.nlm.nih.gov/pubmed/31802598
http://dx.doi.org/10.1111/jcmm.14847
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author Liu, Si‐Yu
Feng, Yi
Wu, Jun-Jie
Zou, Ming-Li
Sun, Zi-Li
Li, Xia
Yuan, Feng‐Lai
author_facet Liu, Si‐Yu
Feng, Yi
Wu, Jun-Jie
Zou, Ming-Li
Sun, Zi-Li
Li, Xia
Yuan, Feng‐Lai
author_sort Liu, Si‐Yu
collection PubMed
description N6‐methyladenosine (m(6)A) is one of the most abundant messenger RNA (mRNA) modifications in eukaryotes and is involved in various key processes of RNA metabolism. In this issue of Nature, Ries et al (2019) described the fundamental features of m6A modification of mRNAs in regulating the composition of the phase‐separated transcriptome on the basis of number and distribution, and provide strong evidence that m6A plays a role in regulating phase separation in cells.
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spelling pubmed-69916612020-02-03 m(6)A facilitates YTHDF‐independent phase separation Liu, Si‐Yu Feng, Yi Wu, Jun-Jie Zou, Ming-Li Sun, Zi-Li Li, Xia Yuan, Feng‐Lai J Cell Mol Med Short Communications N6‐methyladenosine (m(6)A) is one of the most abundant messenger RNA (mRNA) modifications in eukaryotes and is involved in various key processes of RNA metabolism. In this issue of Nature, Ries et al (2019) described the fundamental features of m6A modification of mRNAs in regulating the composition of the phase‐separated transcriptome on the basis of number and distribution, and provide strong evidence that m6A plays a role in regulating phase separation in cells. John Wiley and Sons Inc. 2019-12-04 2020-01 /pmc/articles/PMC6991661/ /pubmed/31802598 http://dx.doi.org/10.1111/jcmm.14847 Text en © 2019 The Authors. Journal of Cellular and Molecular Medicine published by Foundation for Cellular and Molecular Medicine and John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communications
Liu, Si‐Yu
Feng, Yi
Wu, Jun-Jie
Zou, Ming-Li
Sun, Zi-Li
Li, Xia
Yuan, Feng‐Lai
m(6)A facilitates YTHDF‐independent phase separation
title m(6)A facilitates YTHDF‐independent phase separation
title_full m(6)A facilitates YTHDF‐independent phase separation
title_fullStr m(6)A facilitates YTHDF‐independent phase separation
title_full_unstemmed m(6)A facilitates YTHDF‐independent phase separation
title_short m(6)A facilitates YTHDF‐independent phase separation
title_sort m(6)a facilitates ythdf‐independent phase separation
topic Short Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6991661/
https://www.ncbi.nlm.nih.gov/pubmed/31802598
http://dx.doi.org/10.1111/jcmm.14847
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