Cargando…

EZH2 dysregulation: Potential biomarkers predicting prognosis and guiding treatment choice in acute myeloid leukaemia

Accumulating studies have proved EZH2 dysregulation mediated by mutation and expression in diverse human cancers including AML. However, the expression pattern of EZH2 remains controversial in acute myeloid leukaemia (AML). EZH1/2 expression and mutation were analysed in 200 patients with AML. EZH2...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chu, Ming‐qiang, Zhang, Ting‐juan, Xu, Zi‐jun, Gu, Yu, Ma, Ji‐chun, Zhang, Wei, Wen, Xiang‐mei, Lin, Jiang, Qian, Jun, Zhou, Jing‐dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6991666/ https://www.ncbi.nlm.nih.gov/pubmed/31794134 http://dx.doi.org/10.1111/jcmm.14855

Ejemplares similares

Mutations in EZH2 are associated with poor prognosis for patients with myeloid neoplasms
por: Zhang, Qi, et al.
Publicado: (2019)

Dysregulation of miR-200s clusters as potential prognostic biomarkers in acute myeloid leukemia
por: Zhou, Jing-dong, et al.
Publicado: (2018)

Dysregulation of haematopoietic stem cell regulatory programs in acute myeloid leukaemia
por: Basilico, Silvia, et al.
Publicado: (2017)

Chronic myeloid leukaemia with marked thrombocytosis
por: Ooi, Jun, et al.
Publicado: (2020)

EZH2 in Myeloid Malignancies
por: Rinke, Jenny, et al.
Publicado: (2020)

Overexpression of EZH2 in multiple myeloma is associated with poor prognosis and dysregulation of cell cycle control
por: Pawlyn, C, et al.
Publicado: (2017)

Identification and validation of prognosis‐related DLX5 methylation as an epigenetic driver in myeloid neoplasms
por: Zhang, Ting‐juan, et al.
Publicado: (2020)

Dysregulation of LINC00470 and METTL3 promotes chemoresistance and suppresses autophagy of chronic myelocytic leukaemia cells
por: Lai, Xun, et al.
Publicado: (2021)

Comprehensive analysis of SPAG1 expression as a prognostic and predictive biomarker in acute myeloid leukemia by integrative bioinformatics and clinical validation
por: Gu, Yu, et al.
Publicado: (2022)

Dermatoglyphics in childhood leukaemia: a guide to prognosis and aetiology?
por: Till, M., et al.
Publicado: (1978)

Chemotherapy of the Myeloid Leukaemias
por: Stuart, John
Publicado: (1980)

Myeloid dysregulation and therapeutic intervention in COVID-19
por: Gu, Runxia, et al.
Publicado: (2021)

Expression and prognosis analysis of DNMT family in acute myeloid leukemia
por: Zhang, Ting-Juan, et al.
Publicado: (2020)

H19 overexpression promotes leukemogenesis and predicts unfavorable prognosis in acute myeloid leukemia
por: Zhang, Ting-juan, et al.
Publicado: (2018)

Correlations of EZH2 and SMYD3 gene polymorphisms with breast cancer susceptibility and prognosis
por: Ma, Shao-Jun, et al.
Publicado: (2018)

MicroRNA-335/ID4 dysregulation predicts clinical outcome and facilitates leukemogenesis by activating PI3K/Akt signaling pathway in acute myeloid leukemia
por: Zhou, Jing-dong, et al.
Publicado: (2019)

Epigenetic dysregulation of ID4 predicts disease progression and treatment outcome in myeloid malignancies
por: Zhou, Jing‐dong, et al.
Publicado: (2017)

COVID-19 in persons with chronic myeloid leukaemia
por: Li, Weiming, et al.
Publicado: (2020)

Acute Myeloid Leukaemia in Its Niche: the Bone Marrow Microenvironment in Acute Myeloid Leukaemia
por: Ladikou, E. E., et al.
Publicado: (2020)

Up‐regulation of DDIT4 predicts poor prognosis in acute myeloid leukaemia
por: Cheng, Zhiheng, et al.
Publicado: (2019)

Hypermethylation of secreted frizzled-related proteins predicts poor prognosis in non-M3 acute myeloid leukemia
por: Guo, Hong, et al.
Publicado: (2017)

High CX3CR1 expression predicts poor prognosis in paediatric acute myeloid leukaemia undergoing hyperleukocytosis
por: Mei, Nan, et al.
Publicado: (2022)

Erythropoiesis in Murine Myeloid Leukaemia
por: Tanaka, T.
Publicado: (1970)

Desacetylmethylcolchicine in the Treatment of Myeloid Leukaemia
por: Jelliffe, A. M., et al.
Publicado: (1956)

A Case of Myeloid Leukæmia
por: Ghosal, J. N.
Publicado: (1931)

Asciminib for chronic myeloid leukaemia
Publicado: (2022)

Dysregulated lipid metabolism blunts the sensitivity of cancer cells to EZH2 inhibitor
por: Zhang, Tengrui, et al.
Publicado: (2022)

Epigenetic dysregulation of NKD2 is a valuable predictor assessing treatment outcome in acute myeloid leukemia
por: Li, Xi-xi, et al.
Publicado: (2017)

E2F4 functions as a tumour suppressor in acute myeloid leukaemia via inhibition of the MAPK signalling pathway by binding to EZH2
por: Feng, Yubin, et al.
Publicado: (2020)

High bone marrow ID2 expression predicts poor chemotherapy response and prognosis in acute myeloid leukemia
por: Zhou, Jing-Dong, et al.
Publicado: (2017)

A Novel Fatty Acid Metabolism-Associated Risk Model for Prognosis Prediction in Acute Myeloid Leukaemia
por: Wang, Nana, et al.
Publicado: (2023)

Human leukaemia: recent tissue culture studies on the nature of myeloid leukaemia.
por: Metcalf, D.
Publicado: (1973)

IL-8 as mediator in the microenvironment-leukaemia network in acute myeloid leukaemia
por: Kuett, Alexander, et al.
Publicado: (2015)

Site- and allele-specific polycomb dysregulation in T-cell leukaemia
por: Navarro, Jean-Marc, et al.
Publicado: (2015)

Dual roles of EZH2 in acute myeloid leukemia
por: Skoda, Radek C., et al.
Publicado: (2019)

Mutational mechanisms of EZH2 inactivation in myeloid neoplasms
por: Chase, Andrew, et al.
Publicado: (2020)

Myeloid Ezh2 Deficiency Limits Atherosclerosis Development
por: Neele, Annette E., et al.
Publicado: (2021)

Clinical Significance of EZH2 in Acute Myeloid Leukemia
por: Jiao, Weiyun, et al.
Publicado: (2022)

Detection of continuous hierarchical heterogeneity by single-cell surface antigen analysis in the prognosis evaluation of acute myeloid leukaemia
por: Shao, Nan, et al.
Publicado: (2023)

Targeting apoptosis in acute myeloid leukaemia
por: Cassier, Philippe A, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_la64qjc40ehrupldrj4gpqlqhg