Cigarette smoke‐induced HMGB1 translocation and release contribute to migration and NF‐κB activation through inducing autophagy in lung macrophages

High‐mobility group box 1 (HMGB1) shows pro‐inflammatory activity in various inflammatory diseases and has been found up‐regulated in chronic obstructive pulmonary disease (COPD). Lung macrophages play an important role in airway inflammation and lung destruction in COPD, yet whether HMGB1 is involv...

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Detalles Bibliográficos
Autores principales: Le, Yanqing, Wang, Yanhong, Zhou, Lu, Xiong, Jing, Tian, Jieyu, Yang, Xia, Gai, Xiaoyan, Sun, Yongchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6991703/
https://www.ncbi.nlm.nih.gov/pubmed/31769590
http://dx.doi.org/10.1111/jcmm.14789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6991703/
https://www.ncbi.nlm.nih.gov/pubmed/31769590
http://dx.doi.org/10.1111/jcmm.14789

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