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Cigarette smoke‐induced HMGB1 translocation and release contribute to migration and NF‐κB activation through inducing autophagy in lung macrophages
High‐mobility group box 1 (HMGB1) shows pro‐inflammatory activity in various inflammatory diseases and has been found up‐regulated in chronic obstructive pulmonary disease (COPD). Lung macrophages play an important role in airway inflammation and lung destruction in COPD, yet whether HMGB1 is involv...
Autores principales: | Le, Yanqing, Wang, Yanhong, Zhou, Lu, Xiong, Jing, Tian, Jieyu, Yang, Xia, Gai, Xiaoyan, Sun, Yongchang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6991703/ https://www.ncbi.nlm.nih.gov/pubmed/31769590 http://dx.doi.org/10.1111/jcmm.14789 |
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