Landscapes of binding antibody and T-cell responses to pox-protein HIV vaccines in Thais and South Africans

BACKGROUND: HIV vaccine trials routinely measure multiple vaccine-elicited immune responses to compare regimens and study their potential associations with protection. Here we employ unsupervised learning tools facilitated by a bidirectional power transformation to explore the multivariate binding a...

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Detalles Bibliográficos
Autores principales: Zhao, Lue Ping, Fiore-Gartland, Andrew, Carpp, Lindsay N., Cohen, Kristen W., Rouphael, Nadine, Fleurs, Llewellyn, Dintwe, One, Zhao, Michael, Moodie, Zoe, Fong, Youyi, Garrett, Nigel, Huang, Ying, Innes, Craig, Janes, Holly E., Lazarus, Erica, Michael, Nelson L., Nitayaphan, Sorachai, Pitisuttithum, Punnee, Rerks-Ngarm, Supachai, Robb, Merlin L., De Rosa, Stephen C., Corey, Lawrence, Gray, Glenda E., Seaton, Kelly E., Yates, Nicole L., McElrath, M. Juliana, Frahm, Nicole, Tomaras, Georgia D., Gilbert, Peter B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992005/
https://www.ncbi.nlm.nih.gov/pubmed/31999736
http://dx.doi.org/10.1371/journal.pone.0226803

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