Intermittent hypoxia mediated by TSP1 dependent on STAT3 induces cardiac fibroblast activation and cardiac fibrosis

Intermittent hypoxia (IH) is the predominant pathophysiological disturbance in obstructive sleep apnea (OSA), known to be independently associated with cardiovascular diseases. However, the effect of IH on cardiac fibrosis and molecular events involved in this process are unclear. Here, we tested IH...

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Detalles Bibliográficos
Autores principales: Bao, Qiankun, Zhang, Bangying, Suo, Ya, Liu, Chen, Yang, Qian, Zhang, Kai, Yuan, Ming, Yuan, Meng, Zhang, Yue, Li, Guangping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Human Biology and Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992386/
https://www.ncbi.nlm.nih.gov/pubmed/31934850
http://dx.doi.org/10.7554/eLife.49923

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992386/
https://www.ncbi.nlm.nih.gov/pubmed/31934850
http://dx.doi.org/10.7554/eLife.49923

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