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Intermittent hypoxia mediated by TSP1 dependent on STAT3 induces cardiac fibroblast activation and cardiac fibrosis
Intermittent hypoxia (IH) is the predominant pathophysiological disturbance in obstructive sleep apnea (OSA), known to be independently associated with cardiovascular diseases. However, the effect of IH on cardiac fibrosis and molecular events involved in this process are unclear. Here, we tested IH...
Autores principales: | Bao, Qiankun, Zhang, Bangying, Suo, Ya, Liu, Chen, Yang, Qian, Zhang, Kai, Yuan, Ming, Yuan, Meng, Zhang, Yue, Li, Guangping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992386/ https://www.ncbi.nlm.nih.gov/pubmed/31934850 http://dx.doi.org/10.7554/eLife.49923 |
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