Cargando…

Benign adenomyoepitelioma of the breast: Presentation of two rare cases and review of literature

INTRODUCTION: Adenomyoepithelioma of the breast is a rare benign breast neoplasm with a particular behaviour. PRESENTATION OF CASES: We report two cases of adenomyoepithelioma of the breast in two old female patients, diagnosed over a period of 5 years. The clinical presentation, the radiological an...

Descripción completa

Detalles Bibliográficos
Autores principales: Intagliata, Eva, Gangi, Santi, Trovato, Claudio, Vecchio, Rosario, Strazzanti, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992528/
https://www.ncbi.nlm.nih.gov/pubmed/31991375
http://dx.doi.org/10.1016/j.ijscr.2020.01.010
_version_ 1783492845462618112
author Intagliata, Eva
Gangi, Santi
Trovato, Claudio
Vecchio, Rosario
Strazzanti, Angela
author_facet Intagliata, Eva
Gangi, Santi
Trovato, Claudio
Vecchio, Rosario
Strazzanti, Angela
author_sort Intagliata, Eva
collection PubMed
description INTRODUCTION: Adenomyoepithelioma of the breast is a rare benign breast neoplasm with a particular behaviour. PRESENTATION OF CASES: We report two cases of adenomyoepithelioma of the breast in two old female patients, diagnosed over a period of 5 years. The clinical presentation, the radiological and the histopathologic findings are discussed. DISCUSSION: Adenomyoepithelioma of the breast is characterized by the proliferation of both epithelial and myoepithelial cells belonging to the breast lobules and ducts. The imaging features are not pathognomonic and FNAB is usually not diagnostic. The morphologic appearance of this tumor varies, and it has to be considered in the differential diagnosis with other breast tumors. Although benign, adenomyoepithelioma has a potential for local recurrence, and malignant transformation is possible; therefore, wide excision is recommended to lower the recurrence rate. CONCLUSION: The rarity of this histological type and the finding of two cases in a relatively short period makes this case report unique.
format Online
Article
Text
id pubmed-6992528
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-69925282020-02-03 Benign adenomyoepitelioma of the breast: Presentation of two rare cases and review of literature Intagliata, Eva Gangi, Santi Trovato, Claudio Vecchio, Rosario Strazzanti, Angela Int J Surg Case Rep Article INTRODUCTION: Adenomyoepithelioma of the breast is a rare benign breast neoplasm with a particular behaviour. PRESENTATION OF CASES: We report two cases of adenomyoepithelioma of the breast in two old female patients, diagnosed over a period of 5 years. The clinical presentation, the radiological and the histopathologic findings are discussed. DISCUSSION: Adenomyoepithelioma of the breast is characterized by the proliferation of both epithelial and myoepithelial cells belonging to the breast lobules and ducts. The imaging features are not pathognomonic and FNAB is usually not diagnostic. The morphologic appearance of this tumor varies, and it has to be considered in the differential diagnosis with other breast tumors. Although benign, adenomyoepithelioma has a potential for local recurrence, and malignant transformation is possible; therefore, wide excision is recommended to lower the recurrence rate. CONCLUSION: The rarity of this histological type and the finding of two cases in a relatively short period makes this case report unique. Elsevier 2020-01-23 /pmc/articles/PMC6992528/ /pubmed/31991375 http://dx.doi.org/10.1016/j.ijscr.2020.01.010 Text en © 2020 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Intagliata, Eva
Gangi, Santi
Trovato, Claudio
Vecchio, Rosario
Strazzanti, Angela
Benign adenomyoepitelioma of the breast: Presentation of two rare cases and review of literature
title Benign adenomyoepitelioma of the breast: Presentation of two rare cases and review of literature
title_full Benign adenomyoepitelioma of the breast: Presentation of two rare cases and review of literature
title_fullStr Benign adenomyoepitelioma of the breast: Presentation of two rare cases and review of literature
title_full_unstemmed Benign adenomyoepitelioma of the breast: Presentation of two rare cases and review of literature
title_short Benign adenomyoepitelioma of the breast: Presentation of two rare cases and review of literature
title_sort benign adenomyoepitelioma of the breast: presentation of two rare cases and review of literature
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992528/
https://www.ncbi.nlm.nih.gov/pubmed/31991375
http://dx.doi.org/10.1016/j.ijscr.2020.01.010
work_keys_str_mv AT intagliataeva benignadenomyoepiteliomaofthebreastpresentationoftworarecasesandreviewofliterature
AT gangisanti benignadenomyoepiteliomaofthebreastpresentationoftworarecasesandreviewofliterature
AT trovatoclaudio benignadenomyoepiteliomaofthebreastpresentationoftworarecasesandreviewofliterature
AT vecchiorosario benignadenomyoepiteliomaofthebreastpresentationoftworarecasesandreviewofliterature
AT strazzantiangela benignadenomyoepiteliomaofthebreastpresentationoftworarecasesandreviewofliterature