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Dose-Dependent Effects of GLD-2 and GLD-1 on Germline Differentiation and Dedifferentiation in the Absence of PUF-8

PUMILIO/FBF (PUF) proteins have a conserved function in stem cell regulation. Caenorhabditis elegans PUF-8 protein inhibits the translation of target mRNAs by interacting with PUF binding element (PBE) in the 3′ untranslated region (3′ UTR). In this work, an in silico analysis has identified gld-2 [...

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Detalles Bibliográficos
Autores principales: Park, Youngyong, O’Rourke, Samuel, Taki, Faten A., Alfhili, Mohammad A., Lee, Myon Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992537/
https://www.ncbi.nlm.nih.gov/pubmed/32039211
http://dx.doi.org/10.3389/fcell.2020.00005

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